A south St. Louis native, McLaughlin called his first major league game at age 23. His play-by-play work on Cardinals baseball earned him numerous Mid-America Emmy Awards and nominations.

McLaughlin has called SLU Billikens and Missouri Valley Conference basketball game telecasts. He has served as a play-by-play announcer for the NFL and other MLB games on FOX Sports as well. Earlier in his career, he served as host for St. Louis Blues hockey coverage. 

McLaughlin is involved in several local charities and, each October, hosts the Dan McLaughlin Golf Tournament to benefit the Special Education Foundation, which has raised more than $4 million for children with disabilities.

McLaughlin is a 1996 graduate of Lindenwood University, where he played baseball on scholarship. He is an avid golfer and outdoor sportsman. McLaughlin began his professional broadcasting career at KMOX Radio. Dan, his wife Libby and four children make their home in St. Louis.